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Of the above-mentioned ROIs, GSH levels in the frontal (Hupfeld et al., 2021, Tong et al., 2016) and occipital (Emir et al., 2011, Tong et al., 2016) regions were assessed by both MRS and biochemical analyses
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They have binding specificity and affinity comparable to antibodies, along with advantages such as small molecular weight, high structural and nuclease stability, and ease of synthesis and modification ( in vitro transport efficiency was increased by approximately 95%, and absorption in small intestinal Peyer’s patches was significantly enhanced, indicating that aptamer modification can effectively promote M cell-mediated transport and targeted delivery of liposomes ( 2.3 Small-molecule ligand modification In oral liposome delivery systems, to overcome GI barriers and improve drug absorption efficiency, researchers have widely used small-molecule active substances as targeting ligands to modify the liposome surface for active targeting
